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High-Density Genomewide Linkage Analysis of Exceptional Human Longevity Identifies Multiple Novel Loci

BACKGROUND: Human lifespan is approximately 25% heritable, and genetic factors may be particularly important for achieving exceptional longevity. Accordingly, siblings of centenarians have a dramatically higher probability of reaching extreme old age than the general population. METHODOLOGY/PRINCIPA...

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Bibliographic Details
Main Authors: Boyden, Steven E., Kunkel, Louis M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930849/
https://ncbi.nlm.nih.gov/pubmed/20824210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012432
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