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High-Density Genomewide Linkage Analysis of Exceptional Human Longevity Identifies Multiple Novel Loci
BACKGROUND: Human lifespan is approximately 25% heritable, and genetic factors may be particularly important for achieving exceptional longevity. Accordingly, siblings of centenarians have a dramatically higher probability of reaching extreme old age than the general population. METHODOLOGY/PRINCIPA...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930849/ https://ncbi.nlm.nih.gov/pubmed/20824210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012432 |
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