CXCR2 Promotes Ovarian Cancer Growth through Dysregulated Cell Cycle, Diminished Apoptosis, and Enhanced Angiogenesis

PURPOSE: Chemokine receptor CXCR2 is associated with malignancy in several cancer models; however, the mechanisms involved in CXCR2-mediated tumor growth remain elusive. Here, we investigated the role of CXCR2 in human ovarian cancer. EXPERIMENTAL DESIGN: CXCR2 expression was silenced by stable smal...

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Hlavní autoři: Yang, Gong, Rosen, Daniel G., Liu, Guangzhi, Yang, Fan, Guo, Xiaoqing, Xiao, Xue, Xue, Fengxia, Mercado-Uribe, Imelda, Huang, Jiaoti, Lin, Sue-Hwa, Mills, Gordon B., Liu, Jinsong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930833/
https://ncbi.nlm.nih.gov/pubmed/20505188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0483
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