Structural Insights into the Catalytic Mechanism of Bacterial Guanosine-diphospho-d-mannose Pyrophosphorylase and Its Regulation by Divalent Ions

GMP catalyzes the formation of GDP-Man, a fundamental precursor for protein glycosylation and bacterial cell wall and capsular polysaccharide biosynthesis. Crystal structures of GMP from the thermophilic bacterium Thermotoga maritima in the apo form, in complex with the substrates mannose-1-phosphat...

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Hlavní autoři: Pelissier, Marie-Cécile, Lesley, Scott A., Kuhn, Peter, Bourne, Yves
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930745/
https://ncbi.nlm.nih.gov/pubmed/20573954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.095182
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