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Inhibition of STAT3 Signaling Blocks the Anti-apoptotic Activity of IL-6 in Human Liver Cancer Cells

Interleukin-6 (IL-6) is a multifunctional cytokine, which may block apoptosis during inflammation to protect cells under very toxic conditions. However, IL-6 also activates STAT3 in many types of human cancer. Recent studies demonstrate that high levels of IL-6 are associated with hepatocellular car...

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Autores principales: Liu, Yan, Li, Pui-Kai, Li, Chenglong, Lin, Jiayuh
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930741/
https://ncbi.nlm.nih.gov/pubmed/20562100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.142752
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