Ganglioside GD3 Enhances Adhesion Signals and Augments Malignant Properties of Melanoma Cells by Recruiting Integrins to Glycolipid-enriched Microdomains

Ganglioside GD3 is widely expressed in human malignant melanoma cell lines and tumors. Previously, we reported that GD3+ cells show stronger tyrosine phosphorylation of focal adhesion kinase (FAK), p130(Cas), and paxillin when treated with fetal calf serum than GD3− cells. In this study, we analyzed...

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Bibliografiska uppgifter
Huvudupphovsmän: Ohkawa, Yuki, Miyazaki, Sayaka, Hamamura, Kazunori, Kambe, Mariko, Miyata, Maiko, Tajima, Orie, Ohmi, Yuhsuke, Yamauchi, Yoshio, Furukawa, Koichi, Furukawa, Keiko
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2010
Ämnen:
Glycobiology and Extracellular Matrices
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930720/
https://ncbi.nlm.nih.gov/pubmed/20581115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.087791
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