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MicroRNA-221 Regulates Chondrogenic Differentiation through Promoting Proteosomal Degradation of Slug by Targeting Mdm2

MicroRNAs (miRNAs) are small RNAs that fulfill diverse functions by negatively regulating gene expression. Here, we investigated the involvement of miRNAs in the chondrogenic differentiation of chick limb mesenchymal cells and found that the expression of miR-221 increased upon chondrogenic inhibiti...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kim, Dongkyun, Song, Jinsoo, Jin, Eun-Jung
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930689/
https://ncbi.nlm.nih.gov/pubmed/20576614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.115105
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