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MicroRNA-9 regulates survival of chondroblasts and cartilage integrity by targeting protogenin

BACKGROUND: Studies have shown the roles of miR-9 and its validated target, protogenin (PRTG) in the differentiation of chondroblasts to chondrocyte and in the pathogenesis of osteoarthritis (OA). We hypothesized that miR-9 plays a distinct role in endochondral ossification and OA pathogenesis and t...

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Hlavní autoři: Song, Jinsoo, Kim, Dongkyun, Chun, Churl-Hong, Jin, Eun-Jung
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848287/
https://ncbi.nlm.nih.gov/pubmed/24007463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-66
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