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GalR2-positive allosteric modulator exhibits anticonvulsant effects in animal models
Galanin receptors type 1 (GalR1) and/or type 2 (GalR2) represent unique pharmacological targets for treatment of seizures and epilepsy. Previous studies have shown that the endogenous peptide ligand galanin exerts powerful anticonvulsant effect through activation of these two G protein-coupled recep...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930524/ https://ncbi.nlm.nih.gov/pubmed/20660766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008986107 |
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