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Endotoxin impairs cardiac hemodynamics by affecting loading conditions but not by reducing cardiac inotropism
Acute myocardial dysfunction is a typical manifestation of septic shock. Experimentally, the administration of endotoxin [lipopolysacharride (LPS)] to laboratory animals is frequently used to study such dysfunction. However, a majority of studies used load-dependent indexes of cardiac function [incl...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930391/ https://ncbi.nlm.nih.gov/pubmed/20525873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01135.2009 |
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