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Endotoxin impairs cardiac hemodynamics by affecting loading conditions but not by reducing cardiac inotropism

Acute myocardial dysfunction is a typical manifestation of septic shock. Experimentally, the administration of endotoxin [lipopolysacharride (LPS)] to laboratory animals is frequently used to study such dysfunction. However, a majority of studies used load-dependent indexes of cardiac function [incl...

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Main Authors: Jianhui, Li, Rosenblatt-Velin, Nathalie, Loukili, Noureddine, Pacher, Pal, Feihl, François, Waeber, Bernard, Liaudet, Lucas
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930391/
https://ncbi.nlm.nih.gov/pubmed/20525873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01135.2009
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