β-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking
The two widely coexpressed isoforms of β-arrestin (termed βarrestin 1 and 2) are highly similar in amino acid sequence. The β-arrestins bind phosphorylated heptahelical receptors to desensitize and target them to clathrin-coated pits for endocytosis. To better define differences in the roles of β-ar...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2001
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29303/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11171997/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.041608198 |
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