β-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking

The two widely coexpressed isoforms of β-arrestin (termed βarrestin 1 and 2) are highly similar in amino acid sequence. The β-arrestins bind phosphorylated heptahelical receptors to desensitize and target them to clathrin-coated pits for endocytosis. To better define differences in the roles of β-ar...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Kohout, Trudy A., Lin, Fang-Tsyr, Perry, Stephen J., Conner, David A., Lefkowitz, Robert J.
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29303/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11171997/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.041608198
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