NRAS Mutations Are Rare in Colorectal Cancer

Activating mutations in members of the RAS oncogene family (KRAS, HRAS and NRAS) have been found in a variety of human malignancies, suggesting a dominant role in carcinogenesis. In colon cancers, KRAS mutations are common and clearly contribute to malignant progression. The frequency of NRAS mutati...

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Bibliographic Details
Main Authors: Irahara, Natsumi, Baba, Yoshifumi, Nosho, Katsuhiko, Shima, Kaori, Yan, Liying, Dias-Santagata, Dora, Iafrate, A. John, Fuchs, Charles S., Haigis, Kevin M., Ogino, Shuji
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929976/
https://ncbi.nlm.nih.gov/pubmed/20736745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PDM.0b013e3181c93fd1
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