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Heterochromatin silencing at p53 target genes by a small viral protein

The transcription factor p53 guards against tumor and virus replication and is inactivated in almost all cancers. p53 activated transcription of target genes is thought to be synonymous with the stabilization of p53 in response to oncogenes and DNA damage. During adenovirus replication, the degradat...

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Detalles Bibliográficos
Main Authors: Soria, Conrado, Estermann, Fanny E., Espantman, Kristen C., O’Shea, Clodagh C.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929938/
https://ncbi.nlm.nih.gov/pubmed/20740008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09307
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