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RAGE-Independent Autoreactive B Cell Activation In Response To Chromatin And HMGB1/DNA Immune Complexes

Increasing evidence suggests that the excessive accumulation of apoptotic or necrotic cellular debris may contribute to the pathology of systemic autoimmune disease. HMGB1 is a nuclear DNA-associated protein, which can be released from dying cells thereby triggering inflammatory processes. We have p...

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Bibliografiska uppgifter
Huvudupphovsmän: Avalos, Ana M., Kiefer, Kerstin, Tian, Jane, Christensen, Sean, Shlomchik, Mark, Coyle, Anthony J., Marshak-Rothstein, Ann
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929824/
https://ncbi.nlm.nih.gov/pubmed/20014975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08916930903384591
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