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Charge-rich regions modulate the anti-aggregation activity of Hsp90
Protein aggregation can have dramatic effects on cellular function and plays a causative role in many human diseases. In all cells, molecular chaperones bind to aggregation-prone proteins and hinder aggregation. The ability of a protein to resist aggregation and remain soluble in aqueous solution is...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2010
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2929759/ https://ncbi.nlm.nih.gov/pubmed/20615417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.06.066 |
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