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Murine Glut-1 transporter haploinsufficiency: postnatal deceleration of brain weight and reactive astrocytosis

Glucose transporter type 1 (Glut-1) facilitates glucose flux across the blood-brain-barrier. In humans, Glut-1 deficiency causes acquired microcephaly, seizures and ataxia, which are recapitulated in our Glut-1 haploinsufficient mouse model. Postnatal brain weight deceleration and development of rea...

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Detalhes bibliográficos
Main Authors: Ullner, Paivi M., Di Nardo, Alessia, Goldman, James E., Schobel, Scott, Yang, Hong, Engelstad, Kristin, Wang, Dong, Sahin, Mustafa, De Vivo, Darryl C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929707/
https://ncbi.nlm.nih.gov/pubmed/19591936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.06.014
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