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Decorin transfection suppresses profibrogenic genes and myofibroblast formation in human corneal fibroblasts
Decorin, a small leucine-rich proteoglycan, is a natural inhibitor of transforming growth factor beta (TGFβ). Myofibroblast and haze formation in the cornea have been attributed to TGFβ hyperactivity released from corneal epithelium following injury to eye. This study tested the hypothesis that deco...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2929567/ https://ncbi.nlm.nih.gov/pubmed/20546727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2010.05.013 |
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