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Dose and context dependent effects of Myc on epidermal stem cell proliferation and differentiation
Myc is activated in many tumours, yet, paradoxically, stimulates differentiation in mammalian epidermis. To test whether the epidermis responds differently to different levels of Myc, we treated K14MycER transgenic mice with a range of concentrations of the inducing agent, 4-hydroxy-tamoxifen (4OHT)...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
WILEY-VCH Verlag
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2929372/ https://ncbi.nlm.nih.gov/pubmed/20043278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.200900047 |
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