Dose and context dependent effects of Myc on epidermal stem cell proliferation and differentiation

Myc is activated in many tumours, yet, paradoxically, stimulates differentiation in mammalian epidermis. To test whether the epidermis responds differently to different levels of Myc, we treated K14MycER transgenic mice with a range of concentrations of the inducing agent, 4-hydroxy-tamoxifen (4OHT)...

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Detaylı Bibliyografya
Asıl Yazarlar: Berta, Melanie A, Baker, Christopher M, Cottle, Denny L, Watt, Fiona M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: WILEY-VCH Verlag 2010
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929372/
https://ncbi.nlm.nih.gov/pubmed/20043278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.200900047
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