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WHOLE GRAPE INTAKE IMPACTS CARDIAC PPAR AND NF-κB ACTIVITY AND CYTOKINE EXPRESSION IN RATS WITH DIASTOLIC DYSFUNCTION

Prolonged hypertension is the leading cause of heart failure. Failing hearts show reduced peroxisome proliferator-activating receptor activity and enhanced nuclear factor κB activity, which together modify cardiac inflammation and fibrosis. In vitro studies suggest that phytochemicals alter peroxiso...

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Detalhes bibliográficos
Main Authors: Seymour, E Mitchell, Bennink, Maurice R., Watts, Stephanie W., Bolling, Steven F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929369/
https://ncbi.nlm.nih.gov/pubmed/20231522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.109.149393
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