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Jamming the Ratchet of Transcription
The exact mechanism by which cellular RNA polymerases translocate and maintain exceptionally high fidelity during transcription remains a major unresolved issue. Two recent structural studies of yeast RNA polymerase II in complex with its potent inhibitor, the fungal toxin α-amanitin, address this m...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2929366/ https://ncbi.nlm.nih.gov/pubmed/18679430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb0808-777 |
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