Pathogenesis of Hemolytic Anemia in Homozygous Hemoglobin C Disease

Hemoglobin C is less soluble than hemoglobin A in red cells, in hemolysates, and in dilute phosphate buffer. Its relative insolubility may be explained by electrostatic interactions between positively charged β6-lysyl groups and negatively charged groups on adjacent molecules. Red cells from patient...

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Bibliografiska uppgifter

I publikationen:	J Clin Invest
Huvudupphov:	Charache, Samuel, Conley, C. Lockard, Waugh, David F., Ugoretz, Richard J., Spurrell, J. Richard
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Society for Clinical Investigation 1967
Ämnen:	Articles
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC292930/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6061750/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI105670
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