Physiological Activation of Synaptic Rac>PAK (p-21 Activated Kinase) Signaling Is Defective in a Mouse Model of Fragile X Syndrome

The abnormal spine morphology found in fragile X syndrome (FXS) is suggestive of an error in the signaling cascades that organize the actin cytoskeleton. We report here that physiological activation of the small GTPase Rac1 and its effector p-21 activated kinase (PAK), two enzymes critically involve...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Chen, Lulu Y., Rex, Christopher S., Babayan, Alex H., Kramár, Eniko A., Lynch, Gary, Gall, Christine M., Lauterborn, Julie C.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2010
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929244/
https://ncbi.nlm.nih.gov/pubmed/20720104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1077-10.2010
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars