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Asymmetric Alkyl-Alkyl Cross-Couplings of Unactivated Secondary Alkyl Electrophiles: Stereoconvergent Suzuki Reactions of Racemic Acylated Halohydrins

[Image: see text] A method for asymmetric alkyl–alkyl Suzuki reactions of unactivated secondary alkyl electrophiles, specifically, cross-couplings of racemic acylated halohydrins with alkylborane reagents, has been developed. A range of protected bromohydrins, as well as a protected chlorohydrin and...

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Bibliographic Details
Main Authors: Owston, Nathan A., Fu, Gregory C.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929007/
https://ncbi.nlm.nih.gov/pubmed/20701271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja105924f
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