Endothelial α3β1-Integrin Represses Pathological Angiogenesis and Sustains Endothelial-VEGF

Integrin α3β1 is a major receptor for laminin. The expression levels of laminins-8 and -10 in the basement membrane surrounding blood vessels are known to change during tumor angiogenesis. Although some studies have suggested that certain ligands of α3β1 can affect angiogenesis either positively or...

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Main Authors: da Silva, Rita Graça, Tavora, Bernardo, Robinson, Stephen D., Reynolds, Louise E., Szekeres, Charles, Lamar, John, Batista, Sílvia, Kostourou, Vassiliki, Germain, Mitchel A., Reynolds, Andrew R., Jones, Dylan T., Watson, Alan R., Jones, Janet L., Harris, Adrian, Hart, Ian R., Iruela-Arispe, M. Luisa, DiPersio, C. Michael, Kreidberg, Jordan A., Hodivala-Dilke, Kairbaan M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2010
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928983/
https://ncbi.nlm.nih.gov/pubmed/20639457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100043
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