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Cleavage of Osteopontin by Matrix Metalloproteinase-12 Modulates Experimental Autoimmune Encephalomyelitis Disease in C57BL/6 Mice

A role for osteopontin (OPN) in promoting disease activity of multiple sclerosis or its animal model experimental autoimmune encephalomyelitis (EAE) has recently been suggested. As the biological activity of OPN is heavily influenced by posttranslational processing, we investigated the capacity of m...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Goncalves DaSilva, Angelika, Liaw, Lucy, Yong, V. Wee
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Investigative Pathology 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928976/
https://ncbi.nlm.nih.gov/pubmed/20651245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091081
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