Notch3 Overexpression Is Related to the Recurrence of Ovarian Cancer and Confers Resistance to Carboplatin

Amplification of the Notch3 locus has been detected in ovarian high-grade serous carcinoma (HGSC), the most common and malignant type of ovarian cancer. We have previously demonstrated that ovarian cancer cells, which amplified and overexpressed Notch3, were dependent on Notch3 signaling for cellula...

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Главные авторы: Park, Joon Tae, Chen, Xu, Tropè, Claes G., Davidson, Ben, Shih, Ie-Ming, Wang, Tian-Li
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2010
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Regular Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928943/
https://ncbi.nlm.nih.gov/pubmed/20671266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100316
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