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Notch3 Overexpression Is Related to the Recurrence of Ovarian Cancer and Confers Resistance to Carboplatin

Amplification of the Notch3 locus has been detected in ovarian high-grade serous carcinoma (HGSC), the most common and malignant type of ovarian cancer. We have previously demonstrated that ovarian cancer cells, which amplified and overexpressed Notch3, were dependent on Notch3 signaling for cellula...

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Détails bibliographiques
Auteurs principaux: Park, Joon Tae, Chen, Xu, Tropè, Claes G., Davidson, Ben, Shih, Ie-Ming, Wang, Tian-Li
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928943/
https://ncbi.nlm.nih.gov/pubmed/20671266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100316
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