IL-12-STAT4-IFN-γ axis is a key downstream pathway in the development of IL-13-mediated asthma phenotypes in a Th2 type asthma model

IL-4 and IL-13 are closely related cytokines that are produced by Th2 cells. However, IL-4 and IL-13 have different effects on the development of asthma phenotypes. Here, we evaluated downstream molecular mechanisms involved in the development of Th2 type asthma phenotypes. A murine model of Th2 ast...

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Bibliografiska uppgifter
Huvudupphovsmän: Kim, You-Sun, Choi, Seng-Jin, Choi, Jun-Pyo, Jeon, Seong Gyu, Oh, Sun-Young, Lee, Byung-Jae, Gho, Yong Song, Lee, Chun Geun, Zhu, Zhou, Elias, Jack A., Kim, Yoon-Keun
Materialtyp: Artigo
Språk:Inglês
Publicerad: Korean Society for Biochemistry and Molecular Biology 2010
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928926/
https://ncbi.nlm.nih.gov/pubmed/20592486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2010.42.8.054
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