Vitamin D-Binding Protein Directs Monocyte Responses to 25-Hydroxy- and 1,25-Dihydroxyvitamin D

Background: Serum 25-hydroxyvitamin D (25OHD) is a key factor in determining monocyte induction of the antimicrobial protein cathelicidin, which requires intracrine conversion of 25OHD to 1,25-dihydroxyvitamin D [1,25(OH)(2)D]. Both vitamin D metabolites circulate bound to vitamin D-binding protein...

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Autori principali: Chun, Rene F., Lauridsen, Anna L., Suon, Lizabeth, Zella, Lee A., Pike, J. Wesley, Modlin, Robert L., Martineau, Adrian R., Wilkinson, Robert J., Adams, John, Hewison, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928899/
https://ncbi.nlm.nih.gov/pubmed/20427486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-0195
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