PTEN Deletion Enhances the Regenerative Ability of Adult Corticospinal Neurons

Despite the essential role of the corticospinal tract (CST) in controlling voluntary movements, successful regeneration of large numbers of injured CST axons beyond a spinal cord lesion has never been achieved. Here we demonstrate a critical involvement of PTEN/mTOR in controlling the regenerative c...

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Autors principals: Liu, Kai, Lu, Yi, Lee, Jae K., Samara, Ramsey, Willenberg, Rafer, Sears-Kraxberger, Ilse, Tedeschi, Andrea, Park, Kevin Kyungsuk, Jin, Duo, Cai, Bin, Xu, Bengang, Connolly, Lauren, Steward, Oswald, Zheng, Binhai, He, Zhigang
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928871/
https://ncbi.nlm.nih.gov/pubmed/20694004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2603
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