PTEN Deletion Enhances the Regenerative Ability of Adult Corticospinal Neurons

Despite the essential role of the corticospinal tract (CST) in controlling voluntary movements, successful regeneration of large numbers of injured CST axons beyond a spinal cord lesion has never been achieved. Here we demonstrate a critical involvement of PTEN/mTOR in controlling the regenerative c...

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Main Authors: Liu, Kai, Lu, Yi, Lee, Jae K., Samara, Ramsey, Willenberg, Rafer, Sears-Kraxberger, Ilse, Tedeschi, Andrea, Park, Kevin Kyungsuk, Jin, Duo, Cai, Bin, Xu, Bengang, Connolly, Lauren, Steward, Oswald, Zheng, Binhai, He, Zhigang
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928871/
https://ncbi.nlm.nih.gov/pubmed/20694004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2603
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