A Novel CCR5 Mutation Common in Sooty Mangabeys Reveals SIVsmm Infection of CCR5-Null Natural Hosts and Efficient Alternative Coreceptor Use In Vivo

In contrast to HIV infection in humans and SIV in macaques, SIV infection of natural hosts including sooty mangabeys (SM) is non-pathogenic despite robust virus replication. We identified a novel SM CCR5 allele containing a two base pair deletion (Δ2) encoding a truncated molecule that is not expres...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Riddick, Nadeene E., Hermann, Emilia A., Loftin, Lamorris M., Elliott, Sarah T., Wey, Winston C., Cervasi, Barbara, Taaffe, Jessica, Engram, Jessica C., Li, Bing, Else, James G., Li, Yingying, Hahn, Beatrice H., Derdeyn, Cynthia A., Sodora, Donald L., Apetrei, Cristian, Paiardini, Mirko, Silvestri, Guido, Collman, Ronald G.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928783/
https://ncbi.nlm.nih.gov/pubmed/20865163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001064
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars