Neuropeptide delivery to the brain: a von Willebrand factor signal peptide to direct neuropeptide secretion

BACKGROUND: Multiple neuropeptides, sometimes with opposing functions, can be produced from one precursor gene. To study the roles of the different neuropeptides encoded by one large precursor we developed a method to overexpress minigenes and establish local secretion. RESULTS: We fused the signal...

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Autores principales: de Backer, Marijke WA, Brans, Maike AD, Luijendijk, Mieneke CM, Garner, Keith M, van den Heuvel, Dianne MA, Pasterkamp, R Jeroen, Adan, Roger AH
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
Materias:
Methodology Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928777/
https://ncbi.nlm.nih.gov/pubmed/20701764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-94
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