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Recognition of the amber UAG stop codon by release factor RF1

We report the crystal structure of a termination complex containing release factor RF1 bound to the 70S ribosome in response to an amber (UAG) codon at 3.6-Å resolution. The amber codon is recognized in the 30S subunit-decoding centre directly by conserved elements of domain 2 of RF1, including T186...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Korostelev, Andrei, Zhu, Jianyu, Asahara, Haruichi, Noller, Harry F
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928684/
https://ncbi.nlm.nih.gov/pubmed/20588254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.139
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