A multi-stage genome-wide association in breast cancer identifies two novel risk alleles at 1p11.2 and 14q24.1 (RAD51L1)

The Cancer Genetic Markers of Susceptibility (CGEMS) initiative has conducted a three-stage genome-wide association study (GWAS) of breast cancer in 9,770 cases and 10,799 controls. In Stage 1, we genotyped 528,173 single nucleotide polymorphisms (SNPs) in 1,145 cases of invasive breast cancer among...

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Autori principali: Thomas, Gilles, Jacobs, Kevin B., Kraft, Peter, Yeager, Meredith, Wacholder, Sholom, Cox, David G., Hankinson, Susan E., Hutchinson, Amy, Wang, Zhaoming, Yu, Kai, Chatterjee, Nilanjan, Garcia-Closas, Montserrat, Gonzalez-Bosquet, Jesus, Prokunina-Olsson, Ludmila, Orr, Nick, Willett, Walter C., Colditz, Graham A., Ziegler, Regina G., Berg, Christine D., Buys, Saundra S., McCarty, Catherine A., Feigelson, Heather Spencer, Calle, Eugenia E., Thun, Michael J., Diver, Ryan, Prentice, Ross, Jackson, Rebecca, Kooperberg, Charles, Chlebowski, Rowan, Lissowska, Jolanta, Peplonska, Beata, Brinton, Louise A., Sigurdson, Alice, Doody, Michele, Bhatti, Parveen, Alexander, Bruce H., Buring, Julie, Lee, I-Min, Vatten, Lars J, Hveem, Kristian, Kumle, Merethe, Hayes, Richard B., Tucker, Margaret, Gerhard, Daniela S., Fraumeni, Joseph F., Hoover, Robert N., Chanock, Stephen J, Hunter, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928646/
https://ncbi.nlm.nih.gov/pubmed/19330030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.353
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