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Reduced systolic pressure load decreases cell-cycle activity in the fetal sheep heart

The fetal heart is highly sensitive to changes in mechanical load. We have previously demonstrated that increased cardiac load can stimulate cell cycle activity and maturation of immature cardiomyocytes, but the effects of reduced load are not known. Sixteen fetal sheep were given either continuous...

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Detalhes bibliográficos
Main Authors: O'Tierney, P. F., Anderson, D. F., Faber, J. J., Louey, S., Thornburg, K. L., Giraud, G. D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928611/
https://ncbi.nlm.nih.gov/pubmed/20484695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00754.2009
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