Common Genetic Variation in GLP1R and Insulin Secretion in Response to Exogenous GLP-1 in Nondiabetic Subjects: A pilot study

OBJECTIVE: Glucagon-like peptide (GLP)-1 receptor is encoded by GLP1R. The effect of genetic variation at this locus on the response to GLP-1 is unknown. This study assessed the effect of GLP1R polymorphisms on insulin secretion in response to hyperglycemia and to infused GLP-1 in nondiabetic subjec...

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Autors principals: Sathananthan, Airani, Man, Chiara Dalla, Micheletto, Francesco, Zinsmeister, Alan R., Camilleri, Michael, Giesler, Paula D., Laugen, Jeanette M., Toffolo, Gianna, Rizza, Robert A., Cobelli, Claudio, Vella, Adrian
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2010
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928367/
https://ncbi.nlm.nih.gov/pubmed/20805279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc10-0200
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