Centrally Administered Pertussis Toxin Inhibits Microglia Migration to the Spinal Cord and Prevents Dissemination of Disease in an EAE Mouse Model

BACKGROUND: Experimental autoimmune encephalomyelitis (EAE) models are important vehicles for studying the effect of infectious elements such as Pertussis toxin (PTx) on disease processes related to acute demyelinating encephalomyelitis (ADEM) or multiple sclerosis (MS). PTx has pleotropic effects o...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Yin, Jun-xiang, Tu, Jiang-long, Lin, Hao-jie, Shi, Fu-dong, Liu, Ru-lan, Zhao, Chong-bo, Coons, Stephen W., Kuniyoshi, Sandra, Shi, Jiong
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928301/
https://ncbi.nlm.nih.gov/pubmed/20811645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012400
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