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Antimalarial Exposure Delays Plasmodium falciparum Intra-Erythrocytic Cycle and Drives Drug Transporter Genes Expression

BACKGROUND: Multi-drug resistant Plasmodium falciparum is a major obstacle to malaria control and is emerging as a complex phenomenon. Mechanisms of drug evasion based on the intracellular extrusion of the drug and/or modification of target proteins have been described. However, cellular mechanisms...

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Detalhes bibliográficos
Main Authors: Veiga, Maria Isabel, Ferreira, Pedro Eduardo, Schmidt, Berit Aydin, Ribacke, Ulf, Björkman, Anders, Tichopad, Ales, Gil, José Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928296/
https://ncbi.nlm.nih.gov/pubmed/20811640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012408
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