Expression of sterol regulatory element-binding protein 1c (SREBP-1c) mRNA in rat hepatoma cells requires endogenous LXR ligands

The current paper describes a line of cultured rat hepatoma cells (McA-RH7777 cells) that mimics the behavior of rat liver by producing an excess of mRNA for sterol regulatory element-binding protein 1c (SREBP-1c) as opposed to SREBP-1a. These two transcripts are derived from a single gene by use of...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	DeBose-Boyd, Russell A., Ou, Jiafu, Goldstein, Joseph L., Brown, Michael S.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2001
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29282/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11171976/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.4.1477
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