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Allelic exclusion of immunoglobulin genes: models and mechanisms

The allelic exclusion of immunoglobulin (Ig) genes is one of the most evolutionarily conserved features of the adaptive immune system and underlies the monospecificity of B cells. While much has been learned about how Ig allelic exclusion is established during B-cell development, the relevance of mo...

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Detalhes bibliográficos
Main Authors: Vettermann, Christian, Schlissel, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928156/
https://ncbi.nlm.nih.gov/pubmed/20727027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2010.00935.x
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