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Promoter methylation of CDKN2A and lack of p16 expression characterize patients with hepatocellular carcinoma
BACKGROUND: The product of CDKN2A, p16 is an essential regulator of the cell cycle controlling the entry into the S-phase. Herein, we evaluated CDKN2A promoter methylation and p16 protein expression for the differentiation of hepatocellular carcinoma (HCC) from other liver tumors. METHODS: Tumor and...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2927998/ https://ncbi.nlm.nih.gov/pubmed/20569442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-317 |
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