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Association of two functional polymorphisms in the CCR5 gene with juvenile rheumatoid arthritis
Juvenile rheumatoid arthritis (JRA) is mediated by Th1-immune responses. In children with JRA, synovial T-cells express high levels of the Th1-chemokine receptor CCR5, which has been implicated in susceptibility to rheumatoid arthritis. To test the hypothesis that genetic variation in CCR5 is associ...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2927816/ https://ncbi.nlm.nih.gov/pubmed/16775617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gene.6364317 |
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