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Targeting Immune Suppressing Myeloid-Derived Suppressor Cells in Oncology

Emerging data suggests that host immune cells with a suppressive phenotype represent a significant hurdle to successful therapy for metastatic cancer. Among the suppressor cells, T regulatory cells (Treg) and myeloid-derived suppressor cells (MDSC) are significantly increased in hosts with advanced...

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Detalhes bibliográficos
Main Authors: Kao, Johnny, Ko, Eric C., Sikora, Andrew T., Fu, Shibo, Chen, Shu-hsia
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927714/
https://ncbi.nlm.nih.gov/pubmed/20304669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.critrevonc.2010.02.004
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