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Association of the 6q23 region with the rate of joint destruction in rheumatoid arthritis

BACKGROUND: Two novel genetic polymorphisms on chromosome 6q23 are associated with susceptibility to rheumatoid arthritis (RA). Both polymorphisms (rs6920220 and rs10499194) reside in a region close to the gene encoding tumour necrosis factor α-induced protein 3 (TNFAIP3). TNFAIP3 is a negative regu...

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Autors principals: Scherer, Hans Ulrich, van der Linden, Michael P M, Kurreeman, Fina A S, Stoeken-Rijsbergen, Gerrie, le Cessie, Saskia, Huizinga, Tom W J, van der Helm-van Mil, Annette H, Toes, René E M
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927680/
https://ncbi.nlm.nih.gov/pubmed/19366996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2008.106161
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