Improved DNA binding specificity from polyzinc finger peptides by using strings of two-finger units
Multizinc finger peptides are likely to reach increased prominence in the search for the “ideal” designer transcription factor for in vivo applications such as gene therapy. However, for these treatments to be effective and safe, the peptides must bind with high affinity and, more importantly, with...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2001
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29275/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11171969/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.4.1437 |
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