Identification of Attractive Drug Targets in Neglected-Disease Pathogens Using an In Silico Approach

BACKGROUND: The increased sequencing of pathogen genomes and the subsequent availability of genome-scale functional datasets are expected to guide the experimental work necessary for target-based drug discovery. However, a major bottleneck in this has been the difficulty of capturing and integrating...

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Autori principali: Crowther, Gregory J., Shanmugam, Dhanasekaran, Carmona, Santiago J., Doyle, Maria A., Hertz-Fowler, Christiane, Berriman, Matthew, Nwaka, Solomon, Ralph, Stuart A., Roos, David S., Van Voorhis, Wesley C., Agüero, Fernán
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927427/
https://ncbi.nlm.nih.gov/pubmed/20808766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000804
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