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Irinotecan pharmacogenomics

Irinotecan is a camptothecin analog used as an anticancer drug. Severe, potentially life-threatening toxicities can occur from irinotecan treatment. Although multiple genes may play a role in irinotecan activity, the majority of evidence to date suggests that variation in expression of UGT1A1 caused...

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Detalhes bibliográficos
Main Authors: Marsh, Sharon, Hoskins, Janelle M
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927346/
https://ncbi.nlm.nih.gov/pubmed/20602618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.10.95
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